Medical devices at the nanoscale: using structural DNA nanotechnology for nanobiosensing and microrobot self-assembly


March 9, 2018

Thursday, March 8, 2018
Dr. Rebecca Taylor
Carnegie Mellon University
2:00 - 3:00pm
SEH, B1220

 

Abstract

Our lab investigates the mechanics of dynamic micro- and nanoscale structures that have been fabricated using top-down micro- and nanofabrication techniques as well as bottom-up DNA origami techniques. We are interested in studying the mechanics of micro- and nanosystems that are inspired by the structure of the heart and those reconstituted systems that mimic the function of the heart at the molecular and cellular levels. We are also interested in identifying novel applications for DNA nanotechnology, including DNA origami-assisted interfacial communication and nanorobotics.

  • What should nanorobots and nanomachines look like? (would a shear sensor at the nanoscale look like a shear sensor at the microscale?)
  • Can nanomachines organize microsystems?
  • How to we remotely control them?
  • How do we manufacture them with high yield?
  • How to test them to verify yield?
  • How can we make them resistant to the cellular environment (stable against temperature/pH/enzymatic degradation)?